1802.7 (E) Issues Involving Derivative Works
If a work has been changed or revised since it was registered, the changes or revisions cannot be added to the registration record with a supplementary registration. See 37 C.F.R. § 202.6 (D) (4)(ii). Likewise, the Office will not issue a supplementary registration for an entirely new work that has not been registered before (even if it is based on a previously registered work). Instead, the applicant should submit a new application for a new basic registration, together with an appropriate copy(ies) of the new or revised version of the work.
For a definition and discussion of derivative works, see Chapter 500, Section 507.